唐点平

男         

 教育工作经历       

        唐点平，教授，博士生导师，“闽江学者”特聘教授，德国“洪堡学者”，其主要经历如下：  教育经历（按时间倒排序）：

          2005/9 - 2008/6，西南大学，分析化学，博士，导师：袁若

          2002/9 - 2005/6，西南师范大学，分析化学，硕士，导师：袁若

          1997/7 - 2001/6，曲阜师范大学，生物化学，学士

        工作经历（科研与学术工作经历，按时间倒序排序）：

          2009/10 - 至今，福州大学，化学学院，教授 (闽江学者特聘教授)

          2008/7 - 2009/9，德国慕尼黑工业大学，水质化学研究所，博士后，洪堡学者

          1996/7 - 2002/8，山东省枣庄第十五中学，任教

 教学简介   

       本科生课程《生物化学》

       研究生课程《高等分析化学》和《研究方法讲座》

 科研简介   

唐点平，教授，博士/硕士生导师，“闽江学者”特聘教授，德国“洪堡学者”。2008年获西南大学分析化学专业博士学位，同年获德国“洪堡奖学金”资助，在德国慕尼黑工业大学从事博士后研究，2009年底回国，被聘为福州大学“闽江学者”特聘教授，博士生导师。唐点平教授近年来主要从事纳米生物医药及纳米生物传感方面的研究，在肿瘤标志物检测、食品安全分析、环境监测等方面开展了一系列卓有成效的研究，并取得了一系列重要的研究成果，以第一作者或者通讯作者已在Analytical Chemistry、Nano Energy、Nano Letter、Advanced Functional Materials、Clinical Chemistry、Chemical Communication等国际权威刊物上发表SCI论文近200篇。现为Microchimica Acta和Scientific Reports等杂志的国际编委 (2016-2018年曾担任美国Analytical Chemistry杂志编辑顾问委员)。

近五年，本课题组主要围绕免疫分析中捕获抗体的固定方法、信标抗体的标记策略和固定载体等方面进行改进和创新，成功构建一系列新型免疫分析信号放大策略。具体学术成绩主要包括：(1) 在免疫传感探针构建方面：研制新型纳米材料，构建免疫传感界面，制备新型免疫传感探针，用于临床上肿瘤标志物及食品中生物毒素快速、灵敏的检测；(2) 在信标抗体标记技术研究方面：结合纳米标记和生物学技术放大策略，制备新型纳米标记探针，构型多重信号放大免疫分析策略；(3) 在免疫传感模式改进方面：结合物理学和化学生物学知识，构建新型免疫传感分析体系，实现对传统免疫分析模式的革新。

 社会兼职

2016年 – 2018年，美国分析化学《Analytical Chemistry》期刊编委 (SCI)

2015年至今，德国《Microchimica Acta》期刊编委 (SCI)

2013年至今，Nature出版社《Scientific Reports》期刊编审 (SCI)

2015年至今，福建省食品安全促进会专家组成员

 科研项目

       1、国家自然科学基金项目面上项目：基于新型气相敏感器件高灵敏便携式免疫生物传感研究 (2019/01 – 2022/12)，主持

       2、国家自然科学基金项目面上项目：便携式免疫分析模式的构建及其在肿瘤标志物检测中的应用基础研究 (2017/01 – 2020/12)，主持

       3、国家自然科学基金项目面上项目：新型纳米标记探针免疫生物传感对食品中黄曲毒霉素检测新方法研究（2015/01-2018/12），主持，已结

       4、国家自然科学基金项目面上项目：福建邻近海域赤潮毒素磁控生物传感检测技术研究（2012/01-2015/12)，主持，已结题

       5、福建省杰出青年基金滚动项目：免疫分析新方法研究 (2014/11-2017/10) ，主持，已结题

       6、福建省卫生教育联合攻关计划项目: 时序响应的基因/药物共输送纳米载体用于协同治疗肝癌的研究 (2017/01 – 2019/12) ，主持，已结题

        7、国家自然科学基金（国际合作与交流）项目: 新型纳米标记探针在食品和环境样品免疫分析应用中的基础研究 (2012.1-2013.12)，主持，已结题

        8、国家自然科学基金项目面上项目：磁控电化学纳米生物传感在免疫分析化学中应用的基础研究（2011.1-2013.12），主持，已结题

        9、福建省杰出青年基金项目：肿瘤标志物电化学磁免疫分析新方法研究（2011.4-2014.4），主持，已结题

        10、福建省高层次创业创新人才计划（简称“百人计划”） (2014/01 – 2016/12), 主持，已结题

       11、教育部博士点基金项目：磁控生物纳米标记探针的制备及其在生命分析化学中应用的基础研究（2011.1-2013.12），主持，已结题

        12、福州大学校人才基金项目：磁性纳米生物传感在肿瘤标志物检测中应用基础研究，主持，已结题

 代表性论文 

      1. Ruijin Zeng, Jianming Tao, Dianping Tang,* Dietmar Knopp, Jian Shu, Xia Cao,* Biometric-Based Tactile Chemomechanical Transduction: An Adaptable Strategy for Portable Bioassay. Nano Energy 2020, 71, 104580.

      2. Qian Zhou, Dianping Tang,* Recent advances in photoelectrochemical biosensors for analysis of mycotoxins in food. Trends in Analytical Chemistry 2020, 124, 115814.

      3. Lingting Huang, Jialun Chen, Zhonghua Yu, Dianping Tang,* Self-Powered Temperature Sensor with Seebeck Effect Transduction for Photothermal-Thermoelectric Coupled Immunoassay. Analytical Chemistry 2020, 92, 2809-2814.

      4. Shuzhen Lv, Kangyao Zhang, Ling Zhu, Dianping Tang,* ZIF-8-Assisted NaYF4:Yb,Tm@ZnO Converter with Exonuclease III-Powered DNA Walker for Near-Infrared Light Responsive Biosensor. Analytical Chemistry 2020, 92, 1470-1476.

      5.  Jian Shu, Dianping Tang,* Recent Advances in Photoelectrochemical Sensing: From Engineered Photoactive Materials to Sensing Devices and Detection Modes. Analytical Chemistry 2020, 92, 363-377. (Invited Review)

      6.  Shuzhen Lv, Kangyao Zhang, Ling Zhu, Dianping Tang,* Reinhard Niessner,and Dietmar Knopp,* H2-based Electrochemical Biosensor with Pd nanowires@ZIF-67 Molecular Sieve Bilayered Sensing Interface for Immunoassay. Analytical Chemistry 2019, 91, 12055-12062.

      7.  Guoneng Cai, Zhenzhong Yu, Ping Tong,* Dianping Tang,* Ti3C2 MXene quantum dots-encapsulated liposome for photothermal immunoassay using a portable near-infrared imaging camera on smartphone. Nanoscale 2019, 11, 15659-15667.

      8.  Mingdi Xu, Junyang Zhuang,* Xiaoyu Jiang, Xinzhong Liu, Dianping Tang,* Three-dimensional DNA walker amplified FRET sensor for detection of telomerase activity based on MnO2 nanosheets-upconversion nanoparticles senisng platform. Chemical Communications 2019, 55, 9857-9860.

      9.  Zhenzhong Yu, Guoneng Cai, Ping Tong, Dianping Tang* Saw-Toothed Microstructure-Based Flexible Pressure Sensor as the Signal Readout for Point-of-Care Immunoassay. ACS Sensors 2019, 4, 2272-2276.

      10.  Kangyao Zhang, Shuzhen Lv, Dianping Tang,* Novel 3D Printed Device for Dual-Signaling Ratiometric Photoelectrochemical Readout of Biomarker Using λ-Exonuclease-Assisted Recycling Amplification. Analytical Chemistry 2019, 91, 10049-10055.

      11. Ruijin Zeng, Lijia Zhang, Zhongbin Luo, Dianping Tang,* Palindromic Fragment-Mediated Single Chain Amplification: An Innovative Mode for Photoelectrochemical Bioassay. Analytical Chemistry 2019, 91, 7835-7841.

      12.  Lijia Zhang, Zhongbin Luo, Ruijin Zeng, Qian Zhou,* Dianping Tang,* All-solid-state metal-mediated Z-scheme photoelectrochemical immunoassay with enhanced photoexcited charge-separation for monitoring of prostate-specific antigen. Biosensors & Bioelectronics 2019, 134, 1-7.

      13.  Ruijin Zeng, Lijia Zhang, Lingshan Su, Zhongbin Luo, Qian Zhou,* Dianping Tang,* Photoelectrochemical bioanalysis of antibiotics on rGO-Bi2WO6-Au based on branched hybridization chain reaction. Biosensors & Bioelectronics 2019, 133, 100-106.

      14.  Zhongbin Luo, Qingan Qi, Lijia Zhang, Ruijin Zeng, Lingshan Su, Dianping Tang,* Branched Polyethylenimine-Modified Upconversion Nanohybrid-Mediated Photoelectrochemical Immunoassay with Synergistic Effect of Dual-Purpose Copper Ions. Analytical Chemistry 2019, 91, 4149-4156.

      15.  Jian Shu, Zhenli Qiu, Qian Zhou,* Dianping Tang,* Chemiresistive Thin-film Translating Biological Recognition into Electrical Signal: An Innovative Signaling Mode for Contactless Biosensing. Chemical Communications 2019, 55, 3262-3265.

      16.  Ruijin Zeng, Zhongbin Luo, Lingshan Su, Lijia Zhang, Dianping Tang,* Reinhard Niessner, Dietmar Knopp,* Palindromic Molecular Beacon-Based Z-Scheme BiOCl-Au-CdS Photoelectrochemical Biodetection. Analytical Chemistry 2019, 91, 2447-2454.

      17. Zhenzhong Yu, Yun Tang, Guoneng Cai, Rongrong Ren, Dianping Tang,* Paper Electrode-Based Flexible Pressure Sensor for Point-of-Care Immunoassay with Digital Multimeter. Analytical Chemistry 2019, 91, 1220-1226. 

      18.  Zhenli Qiu, Jian Shu, Jingfeng Liu, Dianping Tang,* Dual-channel photoelectrochemical ratiometric aptasensor with up-converting nanocrystals using spatial-resolved technique on homemade 3D printed device. Analytical Chemistry 2019, 91, 1260-1268.

      19.  Shuzhen Lv, Yun Tang, Kangyao Zhang, Dianping Tang,* Wet NH3-Triggered NH2-MIL-125(Ti) Structural Switch for Visible Fluorescence Immunoassay Impregnated on Paper. Analytical Chemistry 2018, 90, 14121-14125.

      20.  Zhenli Qiu, Jian Shu, Dianping Tang,* NaYF4:Yb,Er upconversion nanotransducer with in situ fabrication of Ag2S for near-infrared light responsive photoelectrochemical biosensor. Analytical Chemistry 2018, 90, 12214-12220.

      21.  Ruijin Zeng, Zhongbin Luo, Lijia Zhang, Dianping Tang,* Platinum Nanozyme-Catalyzed Gas Generation for Pressure-Based Bioassay Using Polyaniline Nanowires-Functionalized Graphene Oxide Framework. Analytical Chemistry 2018, 90, 12299-12306.

      22.  Rongrong Ren, Guoneng Cai, Zhenzhong Yu, Yongyi Zeng,* Dianping Tang,* Metal-Polydopamine Framework: An Innovative Signal-Generation Tag for Colorimetric Immunoassay. Analytical Chemistry 2018, 90, 11099-11105.

      23.  Jian Shu, Zhenli Qiu, Dianping Tang,* Self-Referenced Smartphone Imaging for Visual Screening of H2S Using CuxO-Polypyrrole Conductive Aerogel Doped with Graphene Oxide Framework. Analytical Chemistry 2018, 90, 9691-9694.

      24.  Kangyao Zhang, Shuzhen Lv, Minghua Lu,* Dianping Tang,* Photoelectrochemical biosensing of disease marker on p-type Cu-doped Zn0.3Cd0.7S based on RCA and exonuclease III amplification. Biosensors & Bioelectronics 2018, 117, 590-596.

      25.  Zhongbin Luo, Lijia Zhang, Ruijin Zeng,Lingshan Su, Dianping Tang* Near-infrared light-excited core-core-shell UCNP@Au@CdS upconversion nanospheres for ultrasensitive photoelectrochemical enzyme immunoassay. Analytical Chemistry 2018, 90, 9568-9575. 

      26.  Zhenli Qiu, Jian Shu, Dianping Tang,* Plasmonic resonance enhanced photoelectrochemical aptasensor based on g-C3N4/Bi2MoO6. Chemical Communications 2018, 54, 7199-7202.

       27.  Shuzhen Lv, Kangyao Zhang, Yongyi Zeng, Dianping Tang,* Double Photosystems-Based 'Z-Scheme' Photoelectrochemical Sensing Mode for Ultrasensitive Detection of Disease Biomarker Accompanying 3D DNA Walker. Analytical Chemistry 2018, 90, 7086-7093.

       28.  Guoneng Cai, Zhengzhong Yu, Rongrong Ren, Dianping Tang,* Exciton-plasmon interaction between AuNPs/graphene nanohybrids and CdS QDs/TiO2 for photoelectrochemical aptasensing of prostate-specific antigen. ACS Sensors 2018, 3, 632-639.

       29.  Jian Shu, Zhenli Qiu, Shuzhen Lv, Kangyao Zhang, Dianping Tang,* Plasmonic enhancement coupling with defect-engineered TiO2-x: a mode for sensitive photoelectrochemical biosensing. Analytical Chemistry 2018, 90: 2425-2429.

       30.  Zhenli Qiu, Jian Shu, Dianping Tang,* Near-infrared-to-ultraviolet light-mediated photoelectrochemical aptasensing platform for cancer biomarker based on core-shell NaYF4:Yb,Tm@TiO2 upconversion microrods. Analytical Chemistry 2018, 90: 1021-1028.

       31.  Kangyao Zhang, Shuzhen Lv, Zhenzhen Lin, Meijin Li,* Dianping Tang,* Bio-bar-code-based photoelectrochemical immunoassay for sensitive detection of prostate-specific antigen using rolling circle amplification and enzymatic biocatalytic precipitation. Biosensors and Bioelectronics 2018, 101, 159-166.

       32.  Qian Zhou, Youxiu Lin, Kangyao Zhang, Meijin Li,* Dianping Tang,* Reduced graphene oxide/BiFeO3 nanohybrids-based signal-on photoelectrochemical sensing system for prostate-specific antigen detection coupling with magnetic microfluidic device. Biosensors and Bioelectronics 2018, 101, 146-152.

       33.  Shuzhen Lv, Yi Li,* Kangyao Zhang, Zhenzhen Lin, Dianping Tang,* Carbon Dots/g-C3N4 Nanoheterostructures-Based Signal-Generation Tags for Photoelectrochemical Immunoassay of Cancer Biomarkers Coupling with Copper Nanoclusters. ACS Applied Materials & Interfaces 2017, 9, 38336-38343.

       34.  Youxiu Lin, Qian Zhou, Dianping Tang,* Dopamine-Loaded Liposomes for in-Situ Amplified Photoelectrochemical Immunoassay of AFB1 to Enhance Photocurrent of Mn2+-Doped Zn3(OH)2V2O7 Nanobelts. Analytical Chemistry 2017, 89: 11803-11810.

       35.  Jian Shu, Zhenli Qiu, Shuzhen Lv, Kangyao Zhang, Dianping Tang,* Cu2+-Doped SnO2 Nanograin/Polypyrrole Nanospheres with Synergic Enhanced Properties for Ultrasensitive Room-Temperature H2S Gas Sensing. Analytical Chemistry 2017, 89, 11135-11142.

       36.  Jian Shu, Dianping Tang,* Current advances in quantum dots-based photoelectrochemical immunoassays. Chemistry-An Asian Journal 2017, 12, 2780-2789. (Invited Paper)

       37.  Zhuangqiang Gao, Haihang Ye, Dianyong Tang, Jing Tao, Sanaz Habibi, Adrienne Minerick, Dianping Tang, Xiaohu Xia,* Platinum-decorated gold nanoparticles with dual functionalities for ultrasensitive colorimetric in vitro diagnostics. Nano Letters 2017, 17, 5572-5579.

      38.  Qian Zhou, Youxiu Lin, Jian Shu, Kangyao Zhang, Zhenzhong Yu, Dianping Tang,* Reduced graphene oxide-functionalized FeOOH for signal-on photoelectrochemical sensing of prostate-specific antigen with bioresponsive controlled release system. Biosensors and Bioelectronics 2017, 98, 15-21.

      39.  Shuzhen Lv, Kangyao Zhang, Zhenzhen Lin, Dianping Tang,* Novel photoelectrochemical immunosensor for disease-related protein assisted by hemin/G-quadruplex-based DNAzyme on gold nanoparticles to enhance cathodic photocurrent on p-CuBi2O4 semiconductor. Biosensors and Bioelectronics 2017, 96, 317-323.

     40.  Youxin Lin, Qian Zhou, Dianping Tang,* Reinhard Niessner, Dietmar Knopp,* Signal-on photoelectrochemical immunoassay for aflatoxin B1 based on enzymatic product-etching MnO2 nanosheets for dissociation of carbon dots. Analytical Chemistry 2017, 89 (10), 5637-5645.

      41.  Kangyao Zhang, Shuzhen Lv, Zhenzhen Lin, Dianping Tang,* CdS:Mn quantum dot-functionalized g-C3N4 nanohybrids as signal-generation tags for photoelectrochemical immunoassay of prostate specific antigen coupling DNAzyme concatamer with enzymatic biocatalytic precipitation. Biosensors and Bioelectronics 2017, 95, 34-40.

      42.  Zhenli Qiu, Jian Shu, Dianping Tang,* Bioresponsive Release System for Visual Fluorescence Detection of Carcinoembryonic Antigen from Mesoporous Silica Nanocontainers Mediated Optical Color on Quantum Dot-Enzyme-Impregnated Paper. Analytical Chemistry 2017, 89, 5152-5160.

      43.  Zhuangqiang Gao, Grace G. Liu, Haihang Ye, Robert Rauschendorfer, Dianping Tang, Xiaohu Xia,* Facile colorimetric detection of silver ions with picomolar sensitivity. Analytical Chemistry 2017, 89, 3622-3629.

      44.  Zhuangqiang Gao, Zhenli Qiu, Minghua Lu,* Jian Shu, Dianping Tang,* Hybridization chain reaction-based colorimetric aptasensor of adenosine 5'-triphosphate on unmodified gold nanoparticles and two label-free hairpin probes. Biosensors and Bioelectronics 2017, 89P2 (volume 89, Part 2), 1006-1012.

      45.  Wenqiang Lai, Qiaohua Wei,* Mingdi Xu, Junyang Zhuang, Dianping Tang,* Enzyme-controlled dissolution of MnO2 nanoflakes with enzyme cascade amplification for colorimetric immunoassay. Biosensors and Bioelectronics 2017, 89, 645-651.

      46.  Zhenli Qiu, Jian Shu, Yu He,* Zhenzhen Lin, Kangyao Zhang, Shuzhen Lv, and Dianping Tang,* CdTe/CdSe quantum dot-based fluorescent aptasensor with hemin/G-quadruplex DNzyme for sensitive detection of lysozyme using rolling circle amplification and strand hybridization. Biosensors and Bioelectronics 2017, 87, 18-24.

      47.  Ai-Li Sun,* Yan-Fang Zhang, Guo-Peng Sun, Xuan-Nian Wang,* Dianping Tang, Homogeneous electrochemical detection of ochratoxin A in foodstuff using aptamer-graphene oxide nanosheets and DNase I-based target recycling reaction. Biosensors & Bioelectronics 2017, 89, 659-665.

     48.  Jian Shu, Zhenli Qiu, Zhenzhen Lin, Guoneng Cai, Huanghao Yang, Dianping Tang,* Semi-automated support photoelectrochemical immunosensing platform for portable and high-throughput immunoassay based on Au nanocrystal decorated specific crystal facets BiVO4 photoanode. Analytical Chemistry 2016, 88, 12539-12546.

      49.  Qian Zhou, Youxiu Lin, Mingdi Xu, Zhuangqiang Gao, Huanghao Yang, Dianping Tang,* Facile synthesis of enhanced fluorescent gold-silver bimetallic nanocluster and its application for highly sensitive detection of inorganic pyrophosphatase activity. Analytical Chemistry 2016, 88, 8886-8892.

      50.  Mingdi Xu, Zhuangqiang Gao, Qian Zhou, Youxiu Lin, Minghua Lu*, and Dianping Tang* Terbium ion-coordinated carbon dots for fluorescent aptasensing of adenosine 5'-triphosphate with unmodified gold nanoparticles. Biosensors and Bioelectronics 2016, 86, 978-984.

      51.  Youxiu Lin, Qian Zhou, Dianping Tang,* Reinhard Niessner, Huanghao Yang, Dietmar Knopp,* Silver Nanolabels-Assisted Ion-Exchange Reaction with CdTe Quantum Dots Mediated Exciton Trapping for Signal-On Photoelectrochemical Immunoassay of Mycotoxins. Analytical Chemistry 2016, 88, 7858-7866.

      52.  Wenqiang Lai, Qiaohua Wei,* Junyang Zhuang, Minghua Lu,* Dianping Tang, Fenton reaction-based colorimetric immunoassay for sensitive detection of brevetoxin B. Biosensors and Bioelectronics 2016, 80, 249-256.

      53.  Jian Shu, Zhenli Qiu, Qian Zhou, Youxiu Lin, Minghua Lu,* Dianping Tang,* Enzymatic oxydate-triggered self-illuminated photoelectrochemical sensing platform for portable immunoassay using digital multimeter. Analytical Chemistry 2016, 88, 2958-2966. 

      54.  Mingdi Xu, Zhuangqiang Gao, Qiaohua Wei,* Guonan Chen, Dianping Tang,* Label-free hairpin DNA-scaffolded silver nanoclusters for fluorescent detection of Hg2+ using exonuclease III-assisted target recycling amplification. Biosensors and Bioelectronics 2016, 79, 411-415.

      55.  Youxiu Lin, Qian Zhou, Juan Li,* Jian Shu, Zhenli Qiu, Yuping Lin, Dianping Tang,* Magnetic Graphene Nanosheet-Based Microfluidic Device for Homogeneous Real-Time Electronic Monitoring of Pyrophosphatase Activity Using Enzymatic Hydrolysate-Induced Release of Copper Ion. Analytical Chemistry 2016, 88, 1030-1038.

      56.  Qian Zhou, Youxiu Lin, Yuping Lin, Qiaohua Wei,* Guonan Chen, Dianping Tang,* Highly sensitive electrochemical sensing platform for lead ion based on synergetic catalysis of DNAzyme and Au-Pd porous bimetallic nanostructures. Biosensors and Bioelectronics 2016, 78, 236-243.

      57.  Zhenli Qiu, Jian Shu, Guixiao Jin, Mingdi Xu, Qiaohua Wei,* Guonan Chen, Dianping Tang,* Invertase-labeling gold-dendrimer for in situ amplified detection mercury(II) with glucometer readout and thymine-Hg2+-thymine coordination chemistry. Biosensors and Bioelectronics 2016, 77, 681-686.

      58.  Zhenli Qiu, Dianyong Tang,* Jian Shu, Guonan Chen, Dianping Tang,* Enzyme-triggered formation of enzyme-tyramine concatamers on nanogold-functionalized dendrimer for impedimetric detection of Hg(II) with sensitivity enhancement. Biosensors and Bioelectronics 2016, 75, 108-115.

 获奖情况

(1) 2019年，研究论文《Near-infrared-to-ultraviolet light-mediated photoelectrochemical  aptasensing platform for cancer biomarker based on core-shell NaYF4:Yb,Tm@TiO2 upconversion microrods. Analytical Chemistry 2018, 90: 1021-1028》入选2018年中国百篇最具影响国际学术论文；

(2) 2013年入选“世界百名最具影响力分析科学家”荣誉称号；

(3) 2012年获“重庆市自然科学奖一等奖”（排名第三）；

(4) 2011年获“福建省杰出青年基金资助计划”；

(5) 2009年获“福建省“闽江学者”特聘教授”；

(6) 2008年获“德国“洪堡奖学金”资助计划”。

 其他